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Medical Affairs Director, Canada


Position Overview

Exact Sciences is dedicated to delivering patient critical answers across the cancer journey from early detection to treatment decision making. With a strong focus on people and an empathetic spirit, which fuels the company’s culture, driving them to create and deliver solutions rooted in the needs of patients, providers, and families.

From earlier cancer detection to treatment guidance and monitoring, Exact Sciences are helping people get the answers they need to make more informed decisions across the cancer continuum. With a leading portfolio of products for earlier detection and treatment guidance, they help people face the most challenging decisions with confidence with a dedication to continuously innovate, combining scientific rigor with an open-minded approach to deliver the next big thing.

Exact Sciences is continuously expanding the pipeline with the aim of tackling a wider array of cancer tests through the following measures:

  • Expanding the Oncotype IQ platform to include liquid and tissue-based tests, all with the goal of making cancer care smarter.
  • Adapting biomarker-based technologies create a liquid biopsy capable of detecting cancers and precancers from a blood sample.
  • Using their proven multi-marker approach to achieve analytical sensitivity needed to discriminate between normal and cancerous samples.
  • Collaborating with world-class clinicians and scientists at Mayo Clinic to identify biomarkers associated with the 15 deadliest cancers.
  • Building a cancer detection platform upon learnings from the development of Cologuard® (commercially available in the US only).
  • By 2024, Oncotype DX will have been used to guide treatment decisions for more than 2 million cancer patients worldwide in breast, prostate and colon cancer.

    In July 2019 Exact Sciences acquired Genomic Health, a genetic cancer detection company based in Redwood City, California, for USD 2.8 billion, creating the leading global cancer diagnostics company.

    In 2020 Exact Sciences acquired Thrive Earlier Detection Corp., a Massachusetts-based healthcare company, in a multi-billion-dollar deal, and Base Genomics, which has technology for DNA methylation analysis.

    In February 2021 Exact Sciences announced the acquisition of Ashion Analytics, LLC (Ashion) from The Translational Genomics Research Institute (TGen), an affiliate of City of Hope. Ashion is a CLIA-certified and CAP-accredited sequencing lab based in Phoenix, Arizona with the genomics testing capabilities necessary to address the increasingly complex needs of clinical, academic, and biopharma customers focused on precision cancer treatments.

    The company’s global headquarters are in the United States and its International headquarters are in Zug, Switzerland. The International region includes Europe, Canada, Africa, Asia Pacific, Latin America.

    The Medical Affairs Director, Canada is responsible for medical affairs activities in one of the most important markets across International. Representing the medical function, this individual manages research and educational medical objectives, while supporting commercial business and reimbursement objectives for the Oncotype DX portfolio of products, most notably, the Oncotype DX Breast Cancer Assay.Near term business objectives include supporting growth of the breast assay by providing direct support to the market.

    The Medical Affairs Director, Canada plays a key role in providing medical information and education through scientific exchange in a fair-balanced manner to Medical Oncology, Surgeons, and Pathology Key Opinion Leaders as well as other healthcare professionals in breast cancer. In time, they may support other new product introductions in oncology. In addition, the role supports the company’s R&D and investigator-initiated studies in the development and commercialization of genomic assays that lead to improved treatment decisions for oncology patients.

    This position requires professionals with established personal and scientific creditability to interact with thought leaders, government health authorities, and medical centers of excellence.

    Essential Duties

    Include, but are not limited to, the following:

  • Develop a Medical Affairs Strategic Plan for the market, which include plans for Key Opinion Leader engagement, educational and guideline initiatives and reimbursement initiatives that align with the business objectives.
  • Support medical education, reimbursement needs, and physician customer support.
  • Identify and engage international, national, and regional thought leaders in breast cancer within market to conduct scientific discussions and understand insights related to molecular diagnostics in early breast cancer management, while also establishing and maintaining professional relationships with them.
  • Act as primary contact for investigators interested in developing and performing studies with the company’s commercially available assays in breast cancer.
  • Assist/lead in R&D and investigator-initiated studies (e.g. Decision Impact studies) as appropriate.
  • Lead national and regional Advisory Boards when external advice is needed.
  • Execute international medical education and support marketing in accurate, unbiased material development.
  • Provide clinical presentations and information in academic, community, and healthcare provider setting in both group and one-on-one situations.
  • Provide Medical review and edits for all medical, educational and promotional materials
  • Support & partner with regional team to deliver key medical activities.
  • Develop medical slides, give medical training presentations, and training in internal meetings and for partner distributors.
  • Support local access & reimbursement with medical and scientific expertise.
  • Assure compliance with relevant corporate policies and regulatory requirements.
  • Provide feedback and medical input to local commercial plans and strategies
  • Skills

  • Excellent oral, written, and presentation communication skills.
  • Ability to independently deliver quality results in a timely manner.
  • Highest integrity and ethical behavior.
  • Mutual respect for colleagues.
  • Collaborative within teams; uses resources carefully and can build a great place to work and grow.
  • Ability to interact within culturally diverse teams.
  • Business acumen and innovative mindset.
  • Ability to manage though complexity and ambiguity, while focusing on the end goal.
  • Ability to act with an inclusion mindset and model these behaviors for the organization.
  • Maintain regular and reliable attendance.
  • Travel Requirements

  • Ability to travel up to 30% of working time away from work location, may include overnight/weekend travel.
  • Minimum Qualifications

  • Degree in Medicine/Medical Doctor or PhD, PharmD.
  • 3+ years of therapeutic clinical experience desired.
  • 6 to 8 years of industry experience (working in pharma/biotech/med tech).
  • Expertise in Oncology. Experience in breast/GI/lung cancer is a plus.
  • Extensive experience in managing KOLs.
  • Experience in relevant geographies a plus.
  • Excellent French and English mandatory.
  • Excellent oral, written and presentation communication skills.
  • Ability to independently deliver quality results in a timely manner.
  • Proven record of working in matrix environment and delivering as part of a cross-functional team.
  • Track record of delivering innovative medical activities within/across markets.
  • Eligibility to work in Canada without sponsorship.
  • Experience in Diagnostics or Biotech industry is a plus.
  • #LI-CL1

    Présentation du poste

    Exact Sciences a pour mission d'apporter aux patients des réponses essentielles tout au long de leur parcours dans la lutte contre le cancer, depuis la détection précoce jusqu'à la prise de décision concernant le traitement.

    L'accent est mis sur les personnes et l'esprit d'empathie, qui alimente la culture de l'entreprise, les poussant à créer et à fournir des solutions enracinées dans les besoins des patients, des fournisseurs et des familles.

    De la détection précoce du cancer à l'orientation et au suivi du traitement, Exact Sciences aide les gens à obtenir les réponses dont ils ont besoin pour prendre des décisions plus éclairées tout au long du continuum du cancer. Avec un portefeuille de produits de pointe pour la détection précoce et l'orientation du traitement, ils aident les gens à faire face aux décisions les plus difficiles en toute confiance avec un engagement à innover continuellement, en combinant la rigueur scientifique avec une approche ouverte d'esprit pour offrir la prochaine grande chose.

    Exact Sciences élargit continuellement son portefeuille de produits dans le but de s'attaquer à un plus grand nombre de tests de dépistage du cancer grâce aux mesures suivantes :

  • Extension de la plateforme Oncotype IQ pour inclure des tests basés sur les liquides et les tissus, dans le but de rendre les soins du cancer plus intelligents.
  • Adapter les technologies basées sur les biomarqueurs pour créer une biopsie liquide capable de détecter les cancers et les lésions précancéreuses à partir d'un échantillon de sang.
  • Utiliser leur approche multi-marqueurs éprouvée pour atteindre la sensibilité analytique nécessaire pour distinguer les échantillons normaux des échantillons cancéreux.
  • Collaborer avec des cliniciens et des scientifiques de renommée mondiale de la Mayo Clinic pour identifier les biomarqueurs associés aux 15 cancers les plus meurtriers
  • Construire une plateforme de détection du cancer à partir des enseignements tirés du développement de Cologuard® (disponible commercialement aux États-Unis uniquement).
  • D'ici 2022, Oncotype DX aura été utilisé pour guider les décisions thérapeutiques de plus d'un million de patients atteints de cancer du sein, de la prostate et du côlon dans le monde.

    En juillet 2019, Exact Sciences a acquis Genomic Health, une société de détection génétique du cancer basée à Redwood City, en Californie, pour 2,8 milliards de dollars, créant ainsi la première société mondiale de diagnostic du cancer.

    En 2020, Exact Sciences a acquis Thrive Earlier Detection Corp, une société de soins de santé basée dans le Massachusetts, dans le cadre d'une transaction de plusieurs milliards de dollars, et Base Genomics, qui dispose d'une technologie d'analyse de la méthylation de l'ADN.

    En février 2021, Exact Sciences a annoncé l'acquisition d'Ashion Analytics, LLC (Ashion) auprès de The Translational Genomics Research Institute (TGen), une filiale de City of Hope. Ashion est un laboratoire de séquençage certifié CLIA et accrédité CAP basé à Phoenix, en Arizona, qui dispose des capacités de test génomique nécessaires pour répondre aux besoins de plus en plus complexes des clients cliniques, universitaires et biopharmaceutiques axés sur les traitements de précision contre le cancer.

    Le siège mondial de la société se trouve aux États-Unis et son siège international à Zug, en Suisse. La région internationale comprend l'Europe, le Canada, l'Afrique, l'Asie-Pacifique et l'Amérique latine.

    Le directeur des affaires médicales internationales - Canada est responsable des activités liées aux affaires médicales sur l'un des marchés les plus importants de la région internationale.

    Représentant la fonction médicale, cette personne gère la recherche et les objectifs médicaux éducatifs, tout en soutenant les activités commerciales et les objectifs de remboursement pour le portefeuille de produits Oncotype DX, notamment le test Oncotype DX pour le cancer du sein.

    Les objectifs commerciaux à court terme comprennent le soutien à la croissance du test pour le cancer du sein en fournissant un soutien direct au marché.

    Le directeur des affaires médicales - Canada joue un rôle clé dans la fourniture d'informations médicales et d'éducation par le biais d'échanges scientifiques, de manière équilibrée, aux leaders d'opinion en oncologie médicale, en chirurgie et en pathologie, ainsi qu'à d'autres professionnels de la santé dans le domaine du cancer du sein. À terme, ils pourront soutenir d'autres introductions de nouveaux produits en oncologie. En outre, le titulaire du poste soutient la R&D de l'entreprise et les études menées à l'initiative des chercheurs dans le développement et la commercialisation de tests génomiques qui permettent d'améliorer les décisions thérapeutiques pour les patients en oncologie.

    Ce poste requiert des professionnels dont la crédibilité personnelle et scientifique est établie pour interagir avec des leaders d'opinion, des autorités sanitaires gouvernementales et des centres médicaux d'excellence.

    Fonctions essentielles

  • Élaborer un plan stratégique d'affaires médicales pour le marché, comprenant des plans d'engagement des leaders d'opinion, des initiatives en matière d'éducation et de lignes directrices et des initiatives de remboursement qui s'alignent sur les objectifs de l'entreprise.
  • Soutenir la formation médicale, les besoins en matière de remboursement et le soutien des médecins aux clients.
  • Identifier et impliquer les leaders d'opinion internationaux, nationaux et régionaux dans le domaine du cancer du sein au sein du marché afin de mener des discussions scientifiques et de comprendre les idées liées aux diagnostics moléculaires dans la gestion du cancer du sein à un stade précoce, tout en établissant et en entretenant des relations professionnelles avec eux.
  • Servir de contact principal pour les chercheurs intéressés par le développement et la réalisation d'études avec les essais commerciaux de la société dans le domaine du cancer du sein.
  • Assister ou diriger la R&D et les études menées à l'initiative des chercheurs (par exemple, les études d'impact sur les décisions), le cas échéant.
  • Diriger les conseils consultatifs nationaux et régionaux lorsqu'un avis externe est nécessaire.
  • Assurer la formation médicale internationale et soutenir le marketing dans l'élaboration de matériel précis et impartial.
  • Fournir des présentations et des informations cliniques dans les universités, les communautés et les établissements de soins de santé, à la fois en groupe et en tête-à-tête.
  • Assurer la révision médicale et l'édition de tous les documents médicaux, éducatifs et promotionnels.
  • Soutenir et collaborer avec l'équipe régionale pour mener à bien les principales activités médicales.
  • Développer des diapositives médicales, faire des présentations de formation médicale et des formations lors de réunions internes et pour les distributeurs partenaires.
  • Soutenir l'accès et le remboursement au niveau local grâce à son expertise médicale et scientifique.
  • Assurer la conformité avec les politiques de l'entreprise et les exigences réglementaires.
  • Fournir un retour d'information et une contribution médicale aux plans et stratégies commerciales locales.
  • Compétences

  • Excellentes compétences en matière de communication orale, écrite et de présentation.
  • Capacité à fournir de manière autonome des résultats de qualité dans les délais impartis.
  • Intégrité et comportement éthique irréprochables.
  • Respect mutuel des collègues.
  • Esprit de collaboration au sein des équipes ; utilisation prudente des ressources et capacité à créer un lieu de travail et de développement agréable.
  • Capacité à interagir avec des équipes culturellement diverses.
  • Sens des affaires et esprit d'innovation.
  • Capacité à gérer la complexité et l'ambiguïté, tout en se concentrant sur l'objectif final.
  • Capacité à agir dans un esprit d'inclusion et à modéliser ces comportements pour l'organisation.
  • Assiduité et fiabilité. 
  • Exigences en matière de déplacements

  • Capacité à voyager jusqu'à 30 % du temps de travail en dehors du lieu de travail, ce qui peut inclure des déplacements de nuit ou en fin de semaine.
  • Qualifications minimales

  • Diplôme de médecine ou doctorat en médecine ou doctorat en pharmacie.
  • Expérience clinique thérapeutique de plus de 3 ans souhaitée.
  • 6 à 8 ans d'expérience dans l'industrie (pharma/biotech/med tech).
  • Expertise en oncologie. Une expérience dans le domaine du cancer du sein/de l'immunodéficience générale/du poumon est un atout.
  • Vaste expérience de la gestion des experts-conseils. 
  • Une expérience dans les zones géographiques concernées est un plus.
  • Excellente maîtrise du français et de l'anglais obligatoire.
  • Excellentes compétences en matière de communication orale, écrite et de présentation.
  • Capacité à fournir de manière autonome des résultats de qualité dans les délais impartis.
  • Expérience avérée du travail dans un environnement matriciel et au sein d'une équipe interfonctionnelle.
  • Expérience de la mise en œuvre d'activités médicales innovantes au sein des marchés et entre les marchés.
  • Possibilité de travailler au Canada sans parrainage.
  • Une expérience dans l'industrie du diagnostic ou de la biotechnologie est un atout.
  • #LI-CL1

    Our success relies on the experiences and perspectives of a diverse team, and Exact Sciences fosters a culture where all employees can develop personally and professionally with a sense of respect and belonging.


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