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(Associate Director) Principal Clinical Pharmacologist, Cell Therapy Discovery

Company

AstraZeneca

Location

China, Shang Hai Shi

Type

Full time

The Bioanalysis and Translational Medicine department centers on data‑driven bioanalysis and translational research,leveragingmolecular/protein assays, cellular function and phenotyping, and biomarker with PK/PD platforms to support cell therapy programs including CAR‑T and mRNA‑LNP/lentiviral in vivo CAR. 

The Cell Therapy Clinical Pharmacologist leads the development and execution of pharmacology strategies for novelcell therapy,independentlyrepresentingthe department across clinical study and project teams. By applying quantitative principles to cellular kinetics and pharmacodynamics, the individual bridges early research and clinical application tooptimizedosing and minimize unique toxicities like CRS. This role requires rigorous cross-functional collaboration to design, interpret, andreportkey studies—including first-in-human and drug interaction trials—ensuring the efficient advancement of drug candidates through regulatory approval.

  • Lead the design, execution,...

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