Position: Postdoctoral Fellow
Site: Princess Margaret Cancer Centre Research Tower
Department: Princess Margaret Research Institute
Reports to: Principal Investigator
Status: Temporary Full-Time (1 year with possibility of renewal)
University Health Network (UHN) is looking for an experienced professional to fill the key role of a Postdoctoral Fellow in the laboratory of Dr. Shane Harding.
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The University Health Network, where above all else the needs of patients come first, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of groundbreaking firsts and a purpose of Transforming lives and communities through excellence in care, discovery and learning, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.
University Health Network (UHN) is a research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN’s five research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here
A Postdoctoral Fellowship is available immediately for a cell or molecular biologist in the Harding Lab of the Princess Margaret Research Institute at the University Health Network, Toronto, Canada. The position is available for an energetic, highly self-motivated, creative fellow with strong expertise in molecular studies of cancer biology. Broadly the lab is interested in molecular mechanisms of DNA damage signalling. Particularly the focus is on radiotherapy and chemotherapy responses including the inflammatory signaling that contributes to the success of cancer treatment including immunotherapy.
The successful applicant will be expected to bring novel ideas and approaches to the program and contribute to the scientific development of new and existing projects, experimental design, data analysis and manuscript/grant preparation. Experience in tissue culture, molecular biology, and mouse tumour models are required. Experience in NGS (e.g. ChIP-Seq, RNA-Seq), DNA damage response/repair assays or assays of genome organization (FISH, 3C-based methods) will be considered an asset. Recent PhD recipients without previous postdoc experience, who are skilled in molecular biology and cancer research are encouraged to apply. Excellent written and verbal communication skills with the ability to work independently and as a member of a team are required. Interested applicants should submit their C.V., names of three referees and a 1-paragraph statement of research interest.
Please note that only shortlisted candidates will be contacted.
• Ph.D./ M.D. degree in Immunology, Molecular Biology, Genetics, Microbiology or a related field
• Extensive experience with standard molecular biological techniques (Western blot, PCR, cloning) and tissue culture is required
• Experience with handling mice and conducting animal experiments or a willingness to learn
• Experience with confocal microscopy is beneficial
• Experience analyzing RNA-sequencing and gene expression data is beneficial
• Ability to work independently and as part of a team
• Attention to detail and strong organizational skills
• Excellent verbal and written communication skills
• Problem-solving initiative
• Ability to advise/mentor students
Toronto is a vibrant city located on the shores of Lake Ontario. The Princess Margaret Research Institute is located downtown, in the Discovery District, surrounded by four research hospitals and adjacent to the University of Toronto.
If you are interested in making your contribution at UHN, please apply on-line. You will be asked to copy and paste as well as attach your resume, covering letter and contact information for three references. You will also be required to complete some initial screening questions.
POSTED DATE: August 9, 2018
CLOSING DATE: Until Filled
For current UHN employees, only those who have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN’s attendance management program, and possess all the required experience and qualifications should apply.
University Health Network thanks all applicants, however, only those selected for an interview will be contacted.
UHN is a respectful, caring, and inclusive workplace. We are committed to championing accessibility, diversity and equal opportunity. Requests for accommodation can be made at any stage of the recruitment process providing the applicant has met the Bona-fide requirements for the open position. Applicants need to make their requirements known when contacted.